Interactor 1: DTX3L (Q8TDB6)
E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2)
Gene: DTX3L

Interactor 2: DTX3L (Q8TDB6)
E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2)
Gene: DTX3L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 12670957, 35037691, 36197986, 24790097
Identification Methods affinity chromatography technology, biochemical, enzymatic study
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DTC~DTC, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0002230 - positive regulation of defense response to virus by host
GO:0004842 - ubiquitin-protein transferase activity
GO:0004857 - enzyme inhibitor activity
GO:0005634 - nucleus
and 32 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 740
Hs

1 740
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024