HitPredict

Interactor 1: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Interactor 2: RBM4B (Q9BQ04)
RNA-binding protein 4B (RNA-binding motif protein 30) (RNA-binding motif protein 4B) (RNA-binding protein 30)
Gene: RBM4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 359
+	Hs
		1255200 BRX1_HUMAN (1-353): 6.13e-146: 418: 100.00		RBM4_HUMAN (1-359): 9.05e-89: 273: 87.09
+	Hs
		1291763 IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56		RBM4B_HUMAN (1-359): 3.39e-90: 276: 100.00
+	Hs
		1308774 RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83		RBM4B_HUMAN (1-359): 3.39e-90: 276: 100.00
+	Hs
		1308770 RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88		RBM4B_HUMAN (1-359): 3.39e-90: 276: 100.00
+	Hs
		1314619 RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88		RBM4_HUMAN (1-359): 9.05e-89: 273: 87.09
+	Hs
		1308778 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		RBM4B_HUMAN (1-359): 3.39e-90: 276: 100.00
+	Hs
		1314626 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		RBM4_HUMAN (1-359): 9.05e-89: 273: 87.09
+	Sc
		376951 BRX1_YEAST (40-305): 1.92e-92: 279: 45.32		PABP_YEAST (53-263): 4.97e-16: 81: 14.61
+	Sc
		376734 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		PABP_YEAST (53-263): 4.97e-16: 81: 14.61