HitPredict

Interactor 1: EBF2 (Q708Y0)
EIN3-binding F-box protein 2
Gene: EBF2

Interactor 2: CUL1 (Q94AH6)
Cullin-1
Gene: CUL1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	14675533
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cullin~F-box
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0009873 - ethylene-activated signaling pathway GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 At			1 738
+	At
		1375613 GRH1_ARATH (56-571): 5.38e-58: 206: 15.91		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		146319 COI1_ARATH (60-582): 1.32e-54: 197: 14.82		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		1201576 TIR1_ARATH (170-623): 4.81e-25: 111: 15.84		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		1375598 AFB3_ARATH (369-623): 3.65e-15: 80.6: 16.18		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		1375597 SKP2A_ARATH (121-273): 6.19e-15: 78.7: 16.52		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		1375608 EBF1_ARATH (68-303): 1.89e-09: 62.5: 18.39		CUL1_ARATH (1-738): 0: 839: 100.00
+	At
		235566 SKP2B_ARATH (492-622): 2.09e-09: 61.7: 22.70		CUL1_ARATH (1-738): 0: 839: 100.00
+	Hs
		1112595 FXL14_HUMAN (374-622): 7.61e-36: 141: 19.53		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Hs
		1114561 FXL17_HUMAN (89-249): 1.37e-09: 63.2: 16.56		CUL3_HUMAN (1-738): 0: 799: 30.09
+	Hs
		1115056 FXL15_HUMAN (180-395): 1.94e-10: 64.3: 23.15		CUL4A_HUMAN (13-738): 0: 791: 34.61
+	Hs
		1112782 FBXL2_HUMAN (78-354): 8.66e-28: 118: 19.86		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Hs
		1113018 FBXL2_HUMAN (78-354): 8.66e-28: 118: 19.86		CUL2_HUMAN (1-738): 0: 691: 27.05
+	Hs
		1112771 FBXL7_HUMAN (511-623): 8.54e-13: 72.8: 20.49		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Hs
		1112656 FXL20_HUMAN (137-250): 1.33e-10: 65.9: 20.51		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Mm
		1423932 FXL20_MOUSE (137-250): 1.33e-10: 65.9: 20.51		CUL1_MOUSE (4-738): 0: 732: 30.53
+	Hs
		1112780 FBXL4_HUMAN (115-247): 2.16e-10: 65.6: 21.81		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Hs
		1112711 FXL15_HUMAN (180-395): 1.94e-10: 64.3: 23.15		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Hs
		1112763 FXL17_HUMAN (89-249): 1.37e-09: 63.2: 16.56		CUL1_HUMAN (4-738): 0: 732: 30.53
+	Dm
		1173426 Q9VF10_DROME (488-623): 2.03e-09: 62.8: 17.69		CUL1_DROME (3-738): 0: 695: 27.81
+	Sc
		666716 GRR1_YEAST (91-347): 1.17e-15: 82.9: 18.49		CDC53_YEAST (3-738): 0: 598: 21.87