HitPredict

Interactor 1: FXL20 (Q9CZV8)
F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)
Gene: Fbxl20

Interactor 2: CUL1 (Q9WTX6)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	17803915
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cullin~F-box-like
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 436 Mm			1 776
+	Hs
		1112656 FXL20_HUMAN (1-436): 8.79e-99: 304: 99.77		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112782 FBXL2_HUMAN (14-436): 1.68e-87: 274: 77.78		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112598 FBXL6_HUMAN (26-421): 1.86e-50: 180: 20.70		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112771 FBXL7_HUMAN (194-436): 6.23e-36: 140: 26.19		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112595 FXL14_HUMAN (181-435): 4.72e-30: 122: 26.32		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112780 FBXL4_HUMAN (223-423): 3.22e-20: 95.1: 19.83		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1112763 FXL17_HUMAN (226-433): 1.16e-19: 93.4: 20.09		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Hs
		1113018 FBXL2_HUMAN (14-436): 1.68e-87: 274: 77.78		CUL2_HUMAN (13-776): 0: 719: 35.98
+	Hs
		1101806 SKP2_HUMAN (28-280): 6.73e-15: 78.2: 28.94		CUL1_HUMAN (1-776): 0: 909: 99.87
+	Dm
		1173426 Q9VF10_DROME (26-411): 6.1e-52: 188: 26.33		CUL1_DROME (4-776): 0: 770: 61.98
+	Hs
		1113082 SCRIB_HUMAN (186-433): 2.17e-28: 120: 16.53		CUL3_HUMAN (9-776): 0: 747: 30.47
+	At
		1375598 AFB3_ARATH (28-406): 7.88e-35: 138: 19.75		CUL1_ARATH (10-776): 0: 721: 30.29
+	At
		235566 SKP2B_ARATH (223-408): 1.69e-30: 122: 25.93		CUL1_ARATH (10-776): 0: 721: 30.29
+	At
		1375613 GRH1_ARATH (27-419): 1.08e-28: 120: 18.79		CUL1_ARATH (10-776): 0: 721: 30.29
+	Hs
		1114561 FXL17_HUMAN (226-433): 1.16e-19: 93.4: 20.09		CUL3_HUMAN (9-776): 0: 747: 30.47
+	At
		1257723 EBF2_ARATH (195-416): 3.21e-27: 116: 23.02		CUL1_ARATH (10-776): 0: 721: 30.29
+	Hs
		1093225 FLII_HUMAN (246-435): 1.94e-17: 87.2: 11.58		CUL3_HUMAN (9-776): 0: 747: 30.47
+	At
		1375597 SKP2A_ARATH (249-426): 5.86e-26: 109: 28.02		CUL1_ARATH (10-776): 0: 721: 30.29
+	Hs
		1101807 SKP2_HUMAN (28-280): 6.73e-15: 78.2: 28.94		CUL2_HUMAN (13-776): 0: 719: 35.98
+	Sc
		666716 GRR1_YEAST (91-274): 2.98e-20: 95.9: 21.93		CDC53_YEAST (13-776): 0: 628: 31.36