HitPredict - High confidence protein-protein interactions

Interactor 1: Q7K0T0 (Q7K0T0)
LD36178p
Gene: gig

Interactor 2: Q9U9A9 (Q9U9A9)
Tuberous sclerosis gene product-1 homolog
Gene: Tsc1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DUF3384~Hamartin
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0007584 - response to nutrient GO:0008285 - negative regulation of cell population proliferation GO:0008340 - determination of adult lifespan and 16 others more... GO:0016239 - positive regulation of macroautophagy GO:0019900 - kinase binding GO:0019901 - protein kinase binding GO:0030308 - negative regulation of cell growth GO:0032007 - negative regulation of TOR signaling GO:0033596 - TSC1-TSC2 complex GO:0035069 - larval midgut histolysis GO:0042632 - cholesterol homeostasis GO:0045792 - negative regulation of cell size GO:0046621 - negative regulation of organ growth GO:0046627 - negative regulation of insulin receptor signaling pathway GO:0048477 - oogenesis GO:0051726 - regulation of cell cycle GO:0055088 - lipid homeostasis GO:0071456 - cellular response to hypoxia GO:1902350 - cellular response to chloroquine
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1	1876
Dm

1	1100

Service provided by Combinatics, Japan

Last updated: 11Aug2025