HitPredict

Interactor 1: PSD11 (Q7KLV9)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory complex subunit p42B) (26S proteasome regulatory subunit Rpn6)
Gene: Rpn6

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 422 Dm			1 433
+	Hs
		127895 PSD11_HUMAN (2-422): 1.3e-110: 333: 67.93		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Dm
		198047 PSD11_DROME (1-422): 8.14e-116: 346: 100.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Dm
		1267339 PSD11_DROME (1-422): 8.14e-116: 346: 100.00		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Dm
		874971 PSD11_DROME (1-422): 8.14e-116: 346: 100.00		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Dm
		1267353 PSD11_DROME (1-422): 8.14e-116: 346: 100.00		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Hs
		127923 PSD11_HUMAN (2-422): 1.3e-110: 333: 67.93		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		127924 PSD11_HUMAN (2-422): 1.3e-110: 333: 67.93		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		778682 PSMD6_HUMAN (33-415): 7.28e-87: 271: 14.54		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Hs
		127926 PSD11_HUMAN (2-422): 1.3e-110: 333: 67.93		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Hs
		127899 PSD11_HUMAN (2-422): 1.3e-110: 333: 67.93		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Hs
		958616 CSN2_HUMAN (14-419): 5.57e-93: 288: 19.63		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		958617 CSN2_HUMAN (14-419): 5.57e-93: 288: 19.63		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Sc
		751022 RPN6_YEAST (38-421): 3.04e-83: 263: 47.04		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Hs
		968705 PSMD6_HUMAN (33-415): 7.28e-87: 271: 14.54		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		968923 PSMD6_HUMAN (33-415): 7.28e-87: 271: 14.54		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Dm
		198063 PSMD6_DROME (33-415): 8.91e-81: 255: 14.50		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Hs
		975402 PSMD6_HUMAN (33-415): 7.28e-87: 271: 14.54		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Hs
		851321 PSMD6_HUMAN (33-415): 7.28e-87: 271: 14.54		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Sc
		1033909 RPN6_YEAST (38-421): 3.04e-83: 263: 47.04		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Dm
		874994 PSMD6_DROME (33-415): 8.91e-81: 255: 14.50		PRS4_DROME (1-430): 3.95e-117: 351: 38.89