Interactor 1: Q7KSM5 (Q7KSM5)
Activator of SUMO 1 (CG12276 protein) (CG12276-PA) (LD33652p)
Gene: Aos1

Interactor 2: Q7KUA4 (Q7KUA4)
SUMO-activating enzyme subunit
Gene: Uba2

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 10995744, 11884525, 22036573
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ThiF~ThiF, ThiF~UAE_UbL
Common GO terms GO:0002225 - positive regulation of antimicrobial peptide production
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016925 - protein sumoylation
GO:0031510 - SUMO activating enzyme complex
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 337
Dm

1 700
+ Dm
+ Hs
+ Sc
+ Sc
+ Ce
+ Hs
+ Sp
+ Hs
+ Dm
+ Hs
+ Oc
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 11Aug2025