HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: ING1 (Q9UK53)
Inhibitor of growth protein 1
Gene: ING1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.706

The method score is based on:

Property Details
Experiments 11784859, 33961781, 11118440, 15451426, 26949739
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 488
Hs

1 422
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Last updated: 15 Jul 2024