Interactor 1: VPP1 (Q93050)
V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)
Gene: ATP6V0A1

Interactor 2: VATH (Q9UI12)
V-type proton ATPase subunit H (V-ATPase subunit H) (Nef-binding protein 1) (NBP1) (Protein VMA13 homolog) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)
Gene: ATP6V1H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_H_C~V_ATPase_I, V-ATPase_H_N~V_ATPase_I
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007035 - vacuolar acidification
GO:0007042 - lysosomal lumen acidification
and 10 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 837
Hs

1 483
+ Sc
+ Sc

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Last updated: 15 Jul 2024