HitPredict

Interactor 1: Q7SYE2 (Q7SYE2)
Actinin, alpha 4 (Actn4) (Alpha-actinin-4)
Gene: actn4

Interactor 2: MIB1 (Q804S5)
E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Protein mind bomb) (RING-type E3 ubiquitin transferase mib1)
Gene: MIB1

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24714733
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~EF-hand_7
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 901 Dr			1 1030
+	Dr
		1274152 Q7SYD3_DANRE (1-901): 0: 609: 77.69		MIB1_DANRE (1-1030): 0: 866: 100.00
+	Dr
		1180886 Q2YDR5_DANRE (11-901): 0: 604: 77.78		MIB1_DANRE (1-1030): 0: 866: 100.00
+	Hs
		555645 ACTN1_HUMAN (11-901): 0: 643: 86.20		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		224667 ACTN4_HUMAN (1-901): 0: 605: 85.95		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		174752 SPTN2_HUMAN (179-880): 4.63e-22: 105: 13.06		ANK3_HUMAN (638-1021): 1.67e-49: 194: 13.28
+	Hs
		1091395 SPTN1_HUMAN (280-762): 2.45e-17: 89.8: 15.08		ANK3_HUMAN (638-1021): 1.67e-49: 194: 13.28
+	Hs
		1028748 SPTB2_HUMAN (176-764): 2.19e-12: 73.5: 11.17		ANK3_HUMAN (638-1021): 1.67e-49: 194: 13.28
+	Mm
		109265 SPTB2_MOUSE (176-764): 2.76e-12: 73.1: 11.17		ANK3_MOUSE (638-1021): 7.59e-48: 188: 13.28
+	Hs
		1091457 SPTN4_HUMAN (252-801): 3.3e-10: 66.6: 11.25		ANK3_HUMAN (638-1021): 1.67e-49: 194: 13.28
+	Mm
		109260 Q3UGX2_MOUSE (230-865): 1.42e-11: 70.8: 12.20		ANK3_MOUSE (638-1021): 7.59e-48: 188: 13.28
+	Hs
		174745 SPTN2_HUMAN (179-880): 4.63e-22: 105: 13.06		ANK2_HUMAN (673-1021): 3.45e-36: 151: 9.07
+	Hs
		592928 SPTB2_HUMAN (176-764): 2.19e-12: 73.5: 11.17		ANK1_HUMAN (628-1021): 5.2e-44: 176: 12.94
+	Hs
		540235 SPTB1_HUMAN (253-771): 8.84e-10: 65: 10.75		ANK1_HUMAN (628-1021): 5.2e-44: 176: 12.94
+	Hs
		1030639 SPTN1_HUMAN (280-762): 2.45e-17: 89.8: 15.08		ANK2_HUMAN (673-1021): 3.45e-36: 151: 9.07
+	Hs
		174726 SPTN2_HUMAN (179-880): 4.63e-22: 105: 13.06		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		1028731 SPTB2_HUMAN (176-764): 2.19e-12: 73.5: 11.17		ANK2_HUMAN (673-1021): 3.45e-36: 151: 9.07
+	Hs
		920439 SPTN1_HUMAN (280-762): 2.45e-17: 89.8: 15.08		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79
+	Hs
		920429 SPTB2_HUMAN (176-764): 2.19e-12: 73.5: 11.17		DAPK1_HUMAN (419-735): 1.98e-30: 132: 29.79