HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	16189514
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~Arm
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 745
+	Hs
		577716 ANK2_HUMAN (2-500): 6.56e-84: 285: 17.75		PLAK_HUMAN (1-745): 0: 550: 100.00
+	Hs
		764670 ANK2_HUMAN (2-500): 6.56e-84: 285: 17.75		CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38
+	Hs
		634911 BCL3_HUMAN (145-486): 2.54e-73: 240: 32.49		CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38
+	Hs
		764706 ANK3_HUMAN (232-499): 2.06e-65: 231: 24.39		CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38
+	Hs
		577855 Q96F31_HUMAN (29-403): 1.3e-25: 110: 16.15		PLAK_HUMAN (1-745): 0: 550: 100.00
+	Hs
		626099 NFKB1_HUMAN (386-481): 8.68e-13: 72.8: 24.51		CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38
+	Hs
		332388 TNKS1_HUMAN (9-169): 1.47e-11: 69.4: 13.67		CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38
+	Hs
		254180 MIB1_HUMAN (166-500): 4.92e-69: 240: 23.85		CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25
+	Hs
		254126 ANK3_HUMAN (232-499): 2.06e-65: 231: 24.39		CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25
+	Hs
		125891 ANK3_HUMAN (232-499): 2.06e-65: 231: 24.39		ARVC_HUMAN (203-647): 2.39e-15: 82.5: 18.54
+	Hs
		138628 NFKB1_HUMAN (386-481): 8.68e-13: 72.8: 24.51		IMA4_HUMAN (228-670): 1.86e-63: 222: 15.79
+	Hs
		910919 IKBB_HUMAN (254-447): 4.49e-26: 110: 37.50		IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32
+	Hs
		626130 NFKB1_HUMAN (386-481): 8.68e-13: 72.8: 24.51		IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32