HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: Q96F31 (Q96F31)
NF-kappa-B inhibitor epsilon (I-kappa-B-epsilon)
Gene: NFKBIE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	16189514
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Arm
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 423
+	Hs
		634911 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		BCL3_HUMAN (68-409): 1.47e-71: 233: 32.30
+	Hs
		332388 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		TNKS1_HUMAN (153-423): 1.55e-64: 226: 19.65
+	Hs
		626099 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		NFKB1_HUMAN (88-405): 2.1e-35: 140: 18.05
+	Hs
		764706 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		ANK3_HUMAN (255-418): 7.82e-34: 136: 25.00
+	Hs
		577716 PLAK_HUMAN (1-745): 0: 550: 100.00		ANK2_HUMAN (333-422): 3.85e-20: 95.5: 20.00
+	Hs
		764670 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		ANK2_HUMAN (333-422): 3.85e-20: 95.5: 20.00
+	Hs
		127760 PLAK_HUMAN (1-745): 0: 550: 100.00		IKBE_HUMAN (324-414): 6.91e-09: 59.7: 23.66
+	Hs
		254126 CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25		ANK3_HUMAN (255-418): 7.82e-34: 136: 25.00
+	Hs
		254180 CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25		MIB1_HUMAN (148-367): 5.13e-25: 109: 26.01
+	Hs
		138628 IMA4_HUMAN (228-670): 1.86e-63: 222: 15.79		NFKB1_HUMAN (88-405): 2.1e-35: 140: 18.05
+	Hs
		626130 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		NFKB1_HUMAN (88-405): 2.1e-35: 140: 18.05
+	Hs
		910919 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		IKBB_HUMAN (177-370): 2.02e-26: 110: 37.50
+	Hs
		125891 ARVC_HUMAN (203-647): 2.39e-15: 82.5: 18.54		ANK3_HUMAN (255-418): 7.82e-34: 136: 25.00