HitPredict

Interactor 1: Q804D1 (Q804D1)
E3 SUMO-protein ligase CBX4 (Polycomb 2)
Gene: cbx4

Interactor 2: PHC2 (Q8QHL5)
Polyhomeotic-like protein 2
Gene: PHC2

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21195142
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 477 Dr			1 827
+	Hs
		129763 CBX4_HUMAN (1-475): 9.92e-100: 312: 40.57		PHC2_HUMAN (1-827): 5.24e-51: 194: 42.08
+	Hs
		129713 CBX4_HUMAN (1-475): 9.92e-100: 312: 40.57		PHC1_HUMAN (8-827): 1.18e-43: 173: 23.61
+	Hs
		129787 CBX4_HUMAN (1-475): 9.92e-100: 312: 40.57		SCMH1_HUMAN (375-826): 6.73e-37: 149: 17.66
+	Hs
		129830 CBX4_HUMAN (1-475): 9.92e-100: 312: 40.57		SCML2_HUMAN (385-826): 1.89e-26: 117: 16.09
+	Hs
		1132211 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		PHC2_HUMAN (1-827): 5.24e-51: 194: 42.08
+	Hs
		1006845 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		PHC1_HUMAN (8-827): 1.18e-43: 173: 23.61
+	Mm
		721339 CBX2_MOUSE (2-473): 1.52e-68: 229: 20.08		PHC1_MOUSE (8-827): 8.35e-42: 167: 22.96
+	Hs
		1312504 CBX8_HUMAN (1-394): 2.95e-59: 201: 19.37		PHC2_HUMAN (1-827): 5.24e-51: 194: 42.08
+	Hs
		338894 CBX6_HUMAN (1-393): 2.94e-55: 191: 19.80		PHC2_HUMAN (1-827): 5.24e-51: 194: 42.08
+	Hs
		129773 CBX4_HUMAN (1-475): 9.92e-100: 312: 40.57		PHC3_HUMAN (40-735): 3.12e-10: 66: 22.55
+	Hs
		1006879 CBX8_HUMAN (1-394): 2.95e-59: 201: 19.37		PHC1_HUMAN (8-827): 1.18e-43: 173: 23.61
+	Hs
		1132224 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		SCMH1_HUMAN (375-826): 6.73e-37: 149: 17.66
+	Hs
		338809 CBX6_HUMAN (1-393): 2.94e-55: 191: 19.80		PHC1_HUMAN (8-827): 1.18e-43: 173: 23.61
+	Hs
		1391692 CBX8_HUMAN (1-394): 2.95e-59: 201: 19.37		SCMH1_HUMAN (375-826): 6.73e-37: 149: 17.66
+	Hs
		1132248 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		SCML2_HUMAN (385-826): 1.89e-26: 117: 16.09
+	Hs
		1438671 CBX8_HUMAN (1-394): 2.95e-59: 201: 19.37		SCML2_HUMAN (385-826): 1.89e-26: 117: 16.09
+	Hs
		1132251 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		LMBL1_HUMAN (556-788): 1.26e-16: 86.8: 12.40
+	Mm
		721343 CBX2_MOUSE (2-473): 1.52e-68: 229: 20.08		PHC3_MOUSE (6-654): 5.52e-09: 62.2: 10.48
+	Hs
		1132218 CBX2_HUMAN (2-473): 1.21e-66: 225: 20.45		PHC3_HUMAN (40-735): 3.12e-10: 66: 22.55
+	Hs
		1336935 CBX8_HUMAN (1-394): 2.95e-59: 201: 19.37		PHC3_HUMAN (40-735): 3.12e-10: 66: 22.55