HitPredict

Interactor 1: CBX2 (Q14781)
Chromobox protein homolog 2
Gene: CBX2

Interactor 2: SCML2 (Q9UQR0)
Sex comb on midleg-like protein 2
Gene: SCML2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37014752
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0031519 - PcG protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 532 Hs			1 700
+	Hs
		129830 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		SCML2_HUMAN (1-700): 0: 777: 100.00
+	Hs
		1132251 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		LMBL1_HUMAN (129-679): 1.21e-99: 326: 15.98
+	Hs
		1132211 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		PHC2_HUMAN (211-697): 1.08e-85: 289: 15.99
+	Hs
		1006845 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		PHC1_HUMAN (455-696): 4.1e-47: 181: 21.57
+	Hs
		129763 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		PHC2_HUMAN (211-697): 1.08e-85: 289: 15.99
+	Hs
		1132218 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		PHC3_HUMAN (445-697): 4.61e-41: 163: 20.30
+	Mm
		721339 CBX2_MOUSE (1-532): 1.26e-145: 430: 81.84		PHC1_MOUSE (220-696): 2.9e-48: 185: 13.94
+	Mm
		721343 CBX2_MOUSE (1-532): 1.26e-145: 430: 81.84		PHC3_MOUSE (445-697): 5.75e-42: 166: 20.30
+	Hs
		1132246 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		SCML1_HUMAN (471-698): 6.15e-32: 128: 29.54
+	Dr
		1281818 Q804D1_DANRE (3-521): 3.3e-99: 310: 24.04		PHC2_DANRE (253-697): 2.87e-78: 269: 17.04
+	Hs
		1132224 CBX2_HUMAN (1-532): 6.34e-156: 457: 100.00		SCMH1_HUMAN (7-131): 9.71e-23: 105: 32.03
+	Hs
		129713 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		PHC1_HUMAN (455-696): 4.1e-47: 181: 21.57
+	Hs
		129773 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		PHC3_HUMAN (445-697): 4.61e-41: 163: 20.30
+	Hs
		1014175 CBX1_HUMAN (18-153): 1.82e-38: 141: 22.79		LMBL2_HUMAN (2-547): 1.83e-103: 333: 17.64
+	Hs
		129826 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		SCML1_HUMAN (471-698): 6.15e-32: 128: 29.54
+	Hs
		129787 CBX4_HUMAN (3-522): 6.2e-110: 340: 21.89		SCMH1_HUMAN (7-131): 9.71e-23: 105: 32.03
+	Hs
		338894 CBX6_HUMAN (3-242): 2.29e-36: 141: 30.29		PHC2_HUMAN (211-697): 1.08e-85: 289: 15.99
+	Hs
		338809 CBX6_HUMAN (3-242): 2.29e-36: 141: 30.29		PHC1_HUMAN (455-696): 4.1e-47: 181: 21.57
+	Hs
		338909 CBX6_HUMAN (3-242): 2.29e-36: 141: 30.29		PHC3_HUMAN (445-697): 4.61e-41: 163: 20.30
+	Hs
		338930 CBX6_HUMAN (3-242): 2.29e-36: 141: 30.29		SCMH1_HUMAN (7-131): 9.71e-23: 105: 32.03