HitPredict

Interactor 1: KBTB6 (Q86V97)
Kelch repeat and BTB domain-containing protein 6
Gene: KBTBD6

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	21145461, 25684205
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 334
+	Hs
		1326615 KLH36_HUMAN (419-673): 2.46e-39: 155: 15.27		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370358 KLHL4_HUMAN (256-483): 1.19e-26: 117: 14.59		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1199010 KLH12_HUMAN (505-673): 2.53e-25: 112: 13.37		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1333279 KLH23_HUMAN (298-483): 2.24e-23: 106: 19.68		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370428 KLH13_HUMAN (533-673): 3.43e-22: 103: 16.17		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370426 KLHL9_HUMAN (533-673): 5.4e-22: 102: 16.17		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370425 KLHL8_HUMAN (511-673): 8.71e-18: 89.5: 9.41		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1235379 KLH10_HUMAN (551-673): 1.19e-17: 89.1: 15.07		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1247802 KLH24_HUMAN (551-673): 1.88e-13: 75.6: 11.64		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1370446 KLH21_HUMAN (548-673): 6.63e-13: 73.7: 17.61		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		320835 KLH18_HUMAN (596-671): 7.32e-09: 61: 10.10		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		138352 IPP_HUMAN (309-482): 5.13e-26: 114: 19.10		PSDE_HUMAN (50-331): 1.68e-79: 246: 31.51
+	Hs
		131538 KLH20_HUMAN (304-483): 2.76e-25: 113: 17.22		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48