HitPredict

Interactor 1: DTBP1 (Q96EV8)
Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein)
Gene: DTNBP1

Interactor 2: DTNA (Q9Y4J8)
Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)
Gene: DTNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	16448387, 26186194, 28514442, 33961781
Identification Methods	pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030424 - axon GO:0042383 - sarcolemma
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 743
+	Mm
		1265137 DTBP1_MOUSE (1-350): 3.6e-163: 461: 79.43		DTNA_MOUSE (1-743): 0: 876: 94.93
+	Mm
		251084 DTBP1_MOUSE (1-350): 3.6e-163: 461: 79.43		DTNB_MOUSE (1-679): 0: 720: 68.93
+	Hs
		246478 DTBP1_HUMAN (1-351): 4.17e-177: 497: 100.00		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Rn
		950448 DTBP1_RAT (1-350): 1.37e-166: 470: 78.57		DTNB_RAT (1-662): 0: 689: 69.07
+	Rn
		513771 DTBP1_RAT (1-350): 1.37e-166: 470: 78.57		DMD_RAT (14-658): 3.11e-170: 545: 25.49
+	Rn
		223208 DTBP1_RAT (1-350): 1.37e-166: 470: 78.57		O55147_RAT (14-655): 2.17e-159: 513: 23.67