HitPredict

Interactor 1: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Interactor 2: HOOK1 (Q9UJC3)
Protein Hook homolog 1 (h-hook1) (hHK1)
Gene: HOOK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 28718761, 32296183, 32073997, 18799622, 28514442, 33961781, unassigned1304
Identification Methods proximity labelling technology, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HOOK~HOOK, HOOK_N~HOOK_N
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005874 - microtubule
GO:0007032 - endosome organization
GO:0007040 - lysosome organization
and 9 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 718
Hs

1 728
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025