HitPredict

Interactor 1: MIB1 (Q86YT6)
E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)
Gene: MIB1

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~BTB, Ank_2~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1006 Hs			1 727
+	Hs
		318820 MIB1_HUMAN (1-1006): 0: 869: 100.00		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		1295586 MIB1_HUMAN (1-1006): 0: 869: 100.00		IBTK_HUMAN (234-664): 6.88e-81: 283: 17.57
+	Hs
		955105 ANK3_HUMAN (637-997): 1.45e-45: 181: 15.32		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		1091430 ANK3_HUMAN (637-997): 1.45e-45: 181: 15.32		ABTB2_HUMAN (231-647): 1.53e-77: 270: 17.08
+	Hs
		988324 ANK3_HUMAN (637-997): 1.45e-45: 181: 15.32		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		988289 ANK2_HUMAN (618-997): 1.08e-44: 179: 15.99		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		1015396 ANK3_HUMAN (637-997): 1.45e-45: 181: 15.32		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		961998 ANK3_HUMAN (637-997): 1.45e-45: 181: 15.32		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		955746 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		943894 RIPK4_HUMAN (397-718): 1.32e-26: 119: 31.00		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		601494 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RHOQ_HUMAN (10-225): 1.25e-84: 267: 36.53
+	Hs
		962478 Q9H4D1_HUMAN (397-718): 4.05e-26: 117: 31.00		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		581370 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RAC2_HUMAN (12-219): 9.89e-73: 236: 36.97
+	Hs
		953754 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RAC3_HUMAN (12-208): 3.83e-72: 234: 39.50
+	Hs
		988816 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		976655 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RB11A_HUMAN (5-252): 7.95e-71: 232: 16.34
+	Hs
		1015901 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		962626 KDIS_HUMAN (248-507): 2.1e-14: 80.2: 13.45		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Hs
		920420 DAPK1_HUMAN (464-599): 1.59e-10: 67.4: 30.88		RB11A_HUMAN (5-252): 7.95e-71: 232: 16.34