HitPredict

Interactor 1: EHD2 (Q8BH64)
EH domain-containing protein 2
Gene: EHD2

Interactor 2: ANK2 (Q8C8R3)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin)
Gene: ANK2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20489164
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0048471 - perinuclear region of cytoplasm GO:0072659 - protein localization to plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 543 Mm			1 3898
+	Mm
		1298181 EHD1_MOUSE (1-537): 0: 806: 70.76		ANK2_MOUSE (1-3898): 0: 1693: 100.00
+	Mm
		1298177 EHD4_MOUSE (1-543): 0: 788: 67.58		ANK2_MOUSE (1-3898): 0: 1693: 100.00
+	Mm
		1298179 EHD3_MOUSE (1-538): 0: 780: 70.82		ANK2_MOUSE (1-3898): 0: 1693: 100.00
+	Hs
		1030705 EHD2_HUMAN (1-543): 0: 813: 96.69		ANK2_HUMAN (1-3898): 0: 1610: 80.85
+	Hs
		1030693 EHD1_HUMAN (1-537): 0: 805: 71.14		ANK2_HUMAN (1-3898): 0: 1610: 80.85
+	Hs
		1030704 EHD3_HUMAN (1-540): 0: 787: 70.56		ANK2_HUMAN (1-3898): 0: 1610: 80.85
+	Hs
		1030689 EHD4_HUMAN (1-543): 0: 779: 67.58		ANK2_HUMAN (1-3898): 0: 1610: 80.85
+	Hs
		839745 EPS15_HUMAN (451-534): 5.29e-13: 73.9: 27.06		ANK2_HUMAN (1-3898): 0: 1610: 80.85
+	Hs
		1434392 EHD1_HUMAN (1-537): 0: 805: 71.14		ANFY1_HUMAN (599-1288): 4.4e-60: 230: 13.70
+	Hs
		1453482 EHD3_HUMAN (1-540): 0: 787: 70.56		ANFY1_HUMAN (599-1288): 4.4e-60: 230: 13.70
+	Hs
		1091468 EP15R_HUMAN (453-535): 2.39e-09: 62: 28.57		ANK3_HUMAN (2-714): 4.46e-164: 577: 34.31
+	Hs
		274251 ITSN2_HUMAN (444-533): 4.77e-14: 77.4: 39.56		ANR17_HUMAN (11-296): 9.73e-17: 90.5: 31.08