Interactor 1: EXOS3 (Q8IPX7)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: Rrp40

Interactor 2: Q9VGZ2 (Q9VGZ2)
FI06805p (Rrp46)
Gene: Rrp46

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 37061542, unassigned1513, 38944040
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~Rrp40_N, RNase_PH~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
and 4 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 232
Dm

1 233
+ Dm
+ At
+ Hs
+ At
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 11Aug2025