HitPredict

Interactor 1: EXOS6 (Q5RKV6)
Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)
Gene: EXOSC6

Interactor 2: EXOS3 (Q9NQT5)
Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)
Gene: EXOSC3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 24981860, 26186194, 28514442, 33961781, 20531389, 21255825
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RRP40_N_mamm, RNase_PH~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 12 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 272
Hs

1 275
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Service provided by Combinatics, Japan

Last updated: 11Aug2025