HitPredict

Interactor 1: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Interactor 2: TACC3 (Q9Y6A5)
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
Gene: TACC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 838
+	Hs
		281061 MIRO2_HUMAN (1-618): 0: 762: 59.81		TACC1_HUMAN (102-837): 3.74e-37: 151: 25.64
+	Hs
		334308 MIRO2_HUMAN (1-618): 0: 762: 59.81		TACC2_HUMAN (25-837): 1.19e-34: 145: 19.14
+	Hs
		281045 RAB35_HUMAN (5-168): 1.48e-72: 233: 25.90		TACC1_HUMAN (102-837): 3.74e-37: 151: 25.64
+	Hs
		281027 RB11A_HUMAN (5-201): 1.08e-70: 229: 19.60		TACC1_HUMAN (102-837): 3.74e-37: 151: 25.64
+	Hs
		281023 RAC3_HUMAN (3-168): 4.3e-70: 226: 23.89		TACC1_HUMAN (102-837): 3.74e-37: 151: 25.64
+	Hs
		988477 RAC1_HUMAN (3-181): 5.99e-73: 234: 23.83		MICA3_HUMAN (4-822): 9.69e-31: 133: 12.98
+	Hs
		1144980 RAB35_HUMAN (5-168): 1.48e-72: 233: 25.90		MICA3_HUMAN (4-822): 9.69e-31: 133: 12.98
+	Hs
		955951 RAB8A_HUMAN (5-196): 7.57e-71: 229: 18.56		MICA3_HUMAN (4-822): 9.69e-31: 133: 12.98
+	Hs
		976366 RB11A_HUMAN (5-201): 1.08e-70: 229: 19.60		MICA3_HUMAN (4-822): 9.69e-31: 133: 12.98
+	Ce
		145082 RAC1_CAEEL (3-177): 5.62e-72: 231: 23.81		UNC89_CAEEL (38-547): 2.93e-25: 115: 15.08
+	Hs
		319060 RAC1_HUMAN (3-181): 5.99e-73: 234: 23.83		K0754_HUMAN (133-824): 2.94e-23: 109: 12.96
+	Hs
		319066 RAB35_HUMAN (5-168): 1.48e-72: 233: 25.90		K0754_HUMAN (133-824): 2.94e-23: 109: 12.96
+	Hs
		988339 RAC1_HUMAN (3-181): 5.99e-73: 234: 23.83		ROCK1_HUMAN (448-838): 4.46e-15: 81.9: 13.85
+	Hs
		1106267 RAB35_HUMAN (5-168): 1.48e-72: 233: 25.90		ROCK1_HUMAN (448-838): 4.46e-15: 81.9: 13.85
+	Hs
		270795 RAC1_HUMAN (3-181): 5.99e-73: 234: 23.83		ROCK2_HUMAN (401-837): 2.39e-13: 76.5: 9.87
+	Hs
		270793 RB11A_HUMAN (5-201): 1.08e-70: 229: 19.60		ROCK2_HUMAN (401-837): 2.39e-13: 76.5: 9.87
+	Hs
		270789 RAC3_HUMAN (3-168): 4.3e-70: 226: 23.89		ROCK2_HUMAN (401-837): 2.39e-13: 76.5: 9.87
+	Hs
		1123632 RAB35_HUMAN (5-168): 1.48e-72: 233: 25.90		DCTN1_HUMAN (318-752): 2.93e-10: 66.4: 9.65
+	Hs
		955928 RAB8A_HUMAN (5-196): 7.57e-71: 229: 18.56		DCTN1_HUMAN (318-752): 2.93e-10: 66.4: 9.65
+	Sc
		376274 YPT1_YEAST (5-182): 1.14e-70: 228: 19.44		USO1_YEAST (444-837): 4.63e-09: 62.5: 12.32