HitPredict

Interactor 1: SSBP4 (Q9BWG4)
Single-stranded DNA-binding protein 4
Gene: SSBP4

Interactor 2: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781, 30833792
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 385 Hs			1 388
+	Mm
		1321922 SSBP3_MOUSE (6-385): 7.32e-54: 184: 70.03		SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00
+	Hs
		946662 SSBP4_HUMAN (1-385): 6e-71: 228: 100.00		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Mm
		1321887 SSBP3_MOUSE (6-385): 7.32e-54: 184: 70.03		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		946663 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		1314918 SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03		U3KQ46_HUMAN (14-238): 1.16e-36: 135: 62.39
+	Mm
		1321886 SSBP2_MOUSE (1-385): 5.05e-44: 157: 69.77		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Mm
		1111967 SSBP3_MOUSE (6-385): 7.32e-54: 184: 70.03		SMCA4_MOUSE (148-335): 2.53e-10: 64.5: 19.90
+	Hs
		302269 SC24C_HUMAN (90-365): 5.38e-23: 102: 22.38		SC31A_HUMAN (68-362): 6e-27: 114: 17.83
+	Mm
		93247 E9PWQ3_MOUSE (72-168): 1.45e-17: 87: 12.75		E9PWQ3_MOUSE (68-212): 4.93e-21: 97.5: 10.58
+	Mm
		1351630 PCLO_MOUSE (102-359): 6.74e-12: 69.4: 14.13		PCLO_MOUSE (74-360): 6.6e-21: 97.3: 11.00
+	Rn
		358576 CO1A2_RAT (76-334): 1.47e-17: 86.6: 17.24		CO1A1_RAT (72-328): 6.57e-12: 69.4: 14.03
+	Mm
		358670 CO4A1_MOUSE (72-356): 2.67e-14: 76.6: 15.13		CO4A1_MOUSE (129-384): 4.1e-11: 67.1: 15.87
+	Hs
		441078 COLA1_HUMAN (69-358): 3.76e-16: 82.4: 13.69		CO4A2_HUMAN (180-387): 5.1e-09: 60.5: 15.17
+	Dm
		435987 Q9VMV5_DROME (76-287): 9.18e-12: 68.9: 14.95		CO4A1_DROME (214-383): 1.9e-09: 61.7: 13.79
+	Dm
		113976 M9PB30_DROME (91-366): 3.35e-09: 61: 17.57		M9PB30_DROME (81-359): 6.37e-09: 60.3: 19.60
+	Hs
		358624 CO3A1_HUMAN (129-376): 6.72e-09: 60.1: 19.69		CO3A1_HUMAN (79-378): 3.18e-09: 60.9: 16.94