HitPredict

Interactor 1: Q8JID2 (Q8JID2)
Beta-catenin 2 (Catenin, beta 2)
Gene: ctnnb2

Interactor 2: Q9W7C0 (Q9W7C0)
Lymphoid enhancer-binding factor 1
Gene: lef1

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16890162
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~CTNNB1_binding, Arm~HMG_box
Common GO terms	GO:0060070 - canonical Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 778 Dr			1 365
+	Mm
		697743 CTNB1_MOUSE (1-778): 0: 599: 94.62		LEF1_MOUSE (1-365): 3.71e-85: 265: 76.38
+	Hs
		765098 CTNB1_HUMAN (1-778): 0: 600: 94.62		LEF1_HUMAN (1-365): 6.19e-85: 264: 77.75
+	Mm
		1036086 CTNB1_MOUSE (1-778): 0: 599: 94.62		TF7L2_MOUSE (20-355): 1.5e-58: 198: 50.00
+	Xl
		684526 CTNB1_XENLA (1-778): 0: 588: 93.09		T7L1A_XENLA (1-352): 1.99e-59: 202: 46.10
+	Hs
		764490 CTNB1_HUMAN (1-778): 0: 600: 94.62		TCF7_HUMAN (18-364): 9.99e-56: 188: 45.13
+	Hs
		765049 CTNB1_HUMAN (1-778): 0: 600: 94.62		TF7L1_HUMAN (13-339): 3.89e-49: 176: 43.29
+	Mm
		1036104 CTNB1_MOUSE (1-778): 0: 599: 94.62		TF7L1_MOUSE (13-339): 1.65e-49: 176: 42.79
+	Hs
		765055 CTNB1_HUMAN (1-778): 0: 600: 94.62		TF7L2_HUMAN (20-355): 4.1e-48: 173: 44.76
+	Hs
		764535 CTNB1_HUMAN (1-778): 0: 600: 94.62		SOX2_HUMAN (229-362): 7.19e-32: 124: 21.64
+	Hs
		577921 PLAK_HUMAN (8-753): 1.7e-150: 459: 66.93		LEF1_HUMAN (1-365): 6.19e-85: 264: 77.75
+	Hs
		764590 CTNB1_HUMAN (1-778): 0: 600: 94.62		SOX10_HUMAN (171-363): 1.1e-30: 123: 19.59
+	Mm
		872979 CTNB1_MOUSE (1-778): 0: 599: 94.62		SOX2_MOUSE (229-362): 3.54e-30: 119: 21.32
+	Hs
		764487 CTNB1_HUMAN (1-778): 0: 600: 94.62		SOX6_HUMAN (253-335): 2.6e-22: 100: 30.12
+	Mm
		827313 CTNB1_MOUSE (1-778): 0: 599: 94.62		SOX6_MOUSE (253-335): 1.23e-21: 98.4: 30.12
+	Dm
		616517 ARM_DROME (1-738): 1.02e-154: 473: 67.77		PANG1_DROME (1-357): 2.11e-61: 211: 35.29
+	Dm
		616555 ARM_DROME (1-738): 1.02e-154: 473: 67.77		PANG2_DROME (37-357): 5.44e-43: 161: 29.61
+	Hs
		577900 PLAK_HUMAN (8-753): 1.7e-150: 459: 66.93		TF7L2_HUMAN (20-355): 4.1e-48: 173: 44.76
+	Hs
		577865 PLAK_HUMAN (8-753): 1.7e-150: 459: 66.93		CIC_HUMAN (130-350): 1.71e-31: 128: 20.90
+	Ce
		1083569 BAR1_CAEEL (128-746): 5.14e-100: 329: 24.44		POP1_CAEEL (145-356): 1.49e-34: 133: 30.63
+	Ce
		1083565 WRM1_CAEEL (287-456): 3.7e-37: 151: 29.07		POP1_CAEEL (145-356): 1.49e-34: 133: 30.63