HitPredict

Interactor 1: PALS1 (Q8N3R9)
Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1)
Gene: PALS1

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 675 Hs			1 400
+	Mm
		1424313 PALS1_MOUSE (1-675): 0: 579: 96.74		WWTR1_MOUSE (1-400): 7.57e-120: 355: 91.00
+	Mm
		862611 PALS1_MOUSE (1-675): 0: 579: 96.74		YAP1_MOUSE (15-400): 5.46e-100: 307: 41.30
+	Hs
		862291 PALS1_HUMAN (1-675): 0: 581: 100.00		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		1325311 PALS1_HUMAN (1-675): 0: 581: 100.00		WWP1_HUMAN (3-386): 5.13e-64: 222: 13.86
+	Hs
		132160 PALS1_HUMAN (1-675): 0: 581: 100.00		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		1311630 PALS1_HUMAN (1-675): 0: 581: 100.00		KIBRA_HUMAN (123-265): 3.1e-45: 169: 18.88
+	Hs
		1325307 PALS1_HUMAN (1-675): 0: 581: 100.00		MAGI1_HUMAN (10-212): 9.43e-40: 153: 15.74
+	Hs
		861680 PALS1_HUMAN (1-675): 0: 581: 100.00		NEDD4_HUMAN (109-352): 7.43e-23: 103: 11.00
+	Hs
		1325324 PALS1_HUMAN (1-675): 0: 581: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1212193 MPP7_HUMAN (111-674): 3.27e-134: 408: 36.18		KIBRA_HUMAN (123-265): 3.1e-45: 169: 18.88
+	Mm
		1223740 DLG4_MOUSE (10-671): 6.1e-130: 402: 19.60		MAGI3_MOUSE (3-246): 7.57e-44: 165: 18.88
+	Mm
		1223651 DLG4_MOUSE (10-671): 6.1e-130: 402: 19.60		NED4L_MOUSE (129-395): 4.78e-24: 106: 11.96
+	Mm
		97740 DLG4_MOUSE (10-671): 6.1e-130: 402: 19.60		E9PXB7_MOUSE (129-395): 7.94e-23: 102: 12.68
+	Hs
		1091567 DLG1_HUMAN (54-344): 2.11e-18: 92: 13.07		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		862089 DLG1_HUMAN (54-344): 2.11e-18: 92: 13.07		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		1260704 DLG3_HUMAN (256-326): 6.8e-12: 70.8: 20.25		HECW1_HUMAN (14-327): 1.33e-53: 193: 14.29
+	Hs
		1091535 DLG1_HUMAN (54-344): 2.11e-18: 92: 13.07		KIBRA_HUMAN (123-265): 3.1e-45: 169: 18.88
+	Mm
		97734 DLG3_MOUSE (224-326): 7.17e-13: 73.9: 18.02		E9PXB7_MOUSE (129-395): 7.94e-23: 102: 12.68
+	Mm
		861864 DLG3_MOUSE (224-326): 7.17e-13: 73.9: 18.02		NEDD4_MOUSE (129-328): 8.7e-21: 96.6: 10.44
+	Hs
		1368713 DLG3_HUMAN (256-326): 6.8e-12: 70.8: 20.25		NED4L_HUMAN (164-352): 3.04e-13: 73.5: 13.20