HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 196
+	Hs
		132816 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		132808 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		132735 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		132717 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		132804 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		132805 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		132739 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		925382 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900616 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		951099 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		894155 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Mm
		925797 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10
+	Hs
		900762 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915880 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		951207 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892525 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		436297 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Mm
		1111996 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		Q3TLP8_MOUSE (1-196): 9.48e-75: 225: 49.77
+	Hs
		564636 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120433 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98