HitPredict

Interactor 1: ODO1 (P0AFG3)
2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase)
Gene: sucA

Interactor 2: ODO2 (P0AFG6)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)
Gene: sucB

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.856

The method score is based on:

Property Details
Experiments 28524877, 24561554, 15690043
Identification Methods cross-linking study, two hybrid, tandem affinity purification, pull down, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-oxoacid_dh~E1_dh
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006099 - tricarboxylic acid cycle
GO:0045252 - oxoglutarate dehydrogenase complex
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 933
Ec

1 405
+ Hs
+ Mm
+ Ce
+ Hs
+ Sc
+ At
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Dm
+ Bs
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025