HitPredict

Interactor 1: ZBT26 (Q9HCK0)
Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref)
Gene: ZBTB26

Interactor 2: ZBT12 (Q9Y330)
Zinc finger and BTB domain-containing protein 12 (Protein G10)
Gene: ZBTB12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production
GO:0002682 - regulation of immune system process
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 441
Hs

1 459
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024