HitPredict

Interactor 1: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Interactor 2: Q8NEX1 (Q8NEX1)
E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)
Gene: Q8NEX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19690564
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 180
+	Hs
		1338045 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		Q8NEX1_HUMAN (1-180): 7.75e-64: 196: 100.00
+	Hs
		1340074 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		ZNRF2_HUMAN (21-180): 1.37e-53: 172: 100.00
+	Hs
		906711 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		ZNRF2_HUMAN (21-180): 1.37e-53: 172: 100.00
+	Hs
		1336243 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		ZNRF1_HUMAN (12-180): 1.28e-45: 151: 49.46
+	Hs
		906709 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		ZNRF1_HUMAN (12-180): 1.28e-45: 151: 49.46
+	Zm
		77732 B4FC97_MAIZE (1-147): 2.79e-83: 242: 76.19		B6U926_MAIZE (41-180): 1.96e-33: 123: 24.83
+	Zm
		83048 B6SZE0_MAIZE (1-147): 2.64e-83: 242: 75.51		B6U926_MAIZE (41-180): 1.96e-33: 123: 24.83
+	Hs
		1490989 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		RN115_HUMAN (34-178): 3.17e-32: 118: 17.45
+	Hs
		1294294 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		GOLI_HUMAN (109-180): 1.3e-27: 108: 26.39
+	Hs
		1461632 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		RN150_HUMAN (109-180): 1.37e-26: 106: 26.39
+	Hs
		906695 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		GOLI_HUMAN (109-180): 1.3e-27: 108: 26.39
+	Hs
		906823 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		RN150_HUMAN (109-180): 1.37e-26: 106: 26.39
+	Hs
		1414950 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		RN126_HUMAN (10-178): 1.16e-25: 101: 18.39
+	Hs
		906718 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		RN128_HUMAN (101-180): 1.13e-25: 103: 25.00
+	Hs
		906765 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		RN126_HUMAN (10-178): 1.16e-25: 101: 18.39
+	Hs
		1490987 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		RNF11_HUMAN (114-180): 5.27e-22: 88.7: 37.68
+	Hs
		1435277 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		RN167_HUMAN (118-175): 2.33e-10: 60.1: 37.10
+	Hs
		1254114 UB2D4_HUMAN (1-147): 2.21e-83: 243: 91.84		ARK2C_HUMAN (131-175): 2.61e-10: 59.8: 37.78
+	Hs
		906783 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		RN167_HUMAN (118-175): 2.33e-10: 60.1: 37.10
+	Hs
		906686 UB2D1_HUMAN (1-147): 5.09e-83: 241: 100.00		ARK2C_HUMAN (131-175): 2.61e-10: 59.8: 37.78