HitPredict

Interactor 1: NUP43 (Q8NFH3)
Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42)
Gene: NUP43

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Hs			1 1966
+	Hs
		1338986 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		ASH1L_HUMAN (263-1965): 8.82e-72: 270: 10.56
+	Hs
		1339036 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		KMT2B_HUMAN (1069-1966): 4.74e-71: 268: 21.69
+	Hs
		1338944 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		NSD3_HUMAN (1721-1965): 3.92e-68: 256: 24.90
+	Hs
		1041562 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		KMT2A_HUMAN (1173-1966): 2.65e-66: 252: 21.73
+	Hs
		1041577 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		KMT2A_HUMAN (1173-1966): 2.65e-66: 252: 21.73
+	Hs
		1155633 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		EZH2_HUMAN (1460-1950): 4.9e-69: 250: 15.69
+	Hs
		355564 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		NSD2_HUMAN (1654-1965): 3.17e-62: 237: 21.84
+	Hs
		1338943 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SETD2_HUMAN (1733-1965): 3.4e-58: 225: 24.07
+	Hs
		1338903 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		NSD1_HUMAN (1721-1965): 2.39e-57: 223: 23.70
+	Hs
		175912 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		SET1A_HUMAN (409-1966): 4.11e-55: 215: 22.38
+	Hs
		1041589 GRWD1_HUMAN (68-330): 3.43e-56: 192: 15.84		KMT2A_HUMAN (1173-1966): 2.65e-66: 252: 21.73
+	At
		198954 MSI4_ARATH (2-346): 3.82e-59: 201: 13.24		CLF_ARATH (1382-1946): 2.26e-61: 230: 13.30
+	At
		1421791 WDR5A_ARATH (165-380): 1.31e-51: 176: 13.30		ATX1_ARATH (1580-1966): 4.13e-65: 244: 22.76
+	Hs
		175922 GRWD1_HUMAN (68-330): 3.43e-56: 192: 15.84		SET1A_HUMAN (409-1966): 4.11e-55: 215: 22.38
+	Mm
		965395 WDR5_MOUSE (7-245): 2.41e-38: 141: 11.84		KMT2C_MOUSE (1759-1966): 6.68e-58: 225: 36.57
+	Hs
		161493 NUP43_HUMAN (1-380): 1.25e-75: 240: 94.75		KMT2D_HUMAN (1826-1966): 3.09e-17: 91.3: 46.85
+	Hs
		161502 FBXW7_HUMAN (3-371): 9.48e-69: 231: 12.30		KMT2D_HUMAN (1826-1966): 3.09e-17: 91.3: 46.85
+	Hs
		161506 GRWD1_HUMAN (68-330): 3.43e-56: 192: 15.84		KMT2D_HUMAN (1826-1966): 3.09e-17: 91.3: 46.85
+	Hs
		161490 POC1A_HUMAN (159-379): 8.94e-53: 181: 16.52		KMT2D_HUMAN (1826-1966): 3.09e-17: 91.3: 46.85
+	Hs
		161443 WDR5_HUMAN (7-245): 2.41e-38: 141: 11.84		KMT2D_HUMAN (1826-1966): 3.09e-17: 91.3: 46.85