HitPredict

Interactor 1: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.581

Property	Details
Experiments	32552912
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0030424 - axon GO:0030425 - dendrite GO:0031982 - vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 985 Hs			1 639
+	Hs
		1347832 RIN3_HUMAN (1-985): 0: 555: 100.00		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Hs
		1237982 Q6NSK7_HUMAN (1-985): 5.42e-173: 529: 89.14		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Hs
		1347881 RIN3_HUMAN (1-985): 0: 555: 100.00		ITSN2_HUMAN (2-336): 7.69e-44: 171: 18.29
+	Hs
		292853 RIN3_HUMAN (1-985): 0: 555: 100.00		GRAP2_HUMAN (2-330): 4.32e-42: 157: 13.37
+	Hs
		72726 RIN3_HUMAN (1-985): 0: 555: 100.00		B0LPF3_HUMAN (2-168): 2.29e-41: 151: 18.06
+	Hs
		987787 RIN3_HUMAN (1-985): 0: 555: 100.00		GRB2_HUMAN (2-168): 2.29e-41: 151: 18.06
+	Hs
		1154104 Q6NSK7_HUMAN (1-985): 5.42e-173: 529: 89.14		ITSN1_HUMAN (2-336): 1.35e-45: 176: 19.76
+	Hs
		1237986 Q6NSK7_HUMAN (1-985): 5.42e-173: 529: 89.14		ITSN2_HUMAN (2-336): 7.69e-44: 171: 18.29
+	Hs
		1251252 RIN3_HUMAN (1-985): 0: 555: 100.00		DNMBP_HUMAN (1-633): 9.22e-34: 140: 14.11
+	Hs
		594053 RIN3_HUMAN (1-985): 0: 555: 100.00		NCK1_HUMAN (113-396): 2.7e-26: 113: 14.38
+	Hs
		73623 RIN3_HUMAN (1-985): 0: 555: 100.00		B2R6S4_HUMAN (113-396): 3.11e-26: 113: 14.38
+	Hs
		594023 Q6NSK7_HUMAN (1-985): 5.42e-173: 529: 89.14		NCK1_HUMAN (113-396): 2.7e-26: 113: 14.38
+	Hs
		250295 RIN3_HUMAN (1-985): 0: 555: 100.00		VINEX_HUMAN (163-343): 1.32e-12: 72.7: 18.18
+	Hs
		1216073 RIN3_HUMAN (1-985): 0: 555: 100.00		SPD2A_HUMAN (61-291): 1.07e-09: 63.7: 13.50
+	Hs
		1462487 MACF1_HUMAN (595-857): 3.27e-44: 177: 15.83		CD2AP_HUMAN (1-639): 1.27e-133: 407: 100.00
+	Hs
		176275 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Hs
		176266 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		ITSN1_HUMAN (2-336): 1.35e-45: 176: 19.76
+	Hs
		176277 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		ITSN2_HUMAN (2-336): 7.69e-44: 171: 18.29
+	Hs
		176259 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		GRB2_HUMAN (2-168): 2.29e-41: 151: 18.06
+	Hs
		176246 SYNJ2_HUMAN (181-535): 2.14e-27: 122: 16.89		NCK1_HUMAN (113-396): 2.7e-26: 113: 14.38