HitPredict

Interactor 1: EHD3 (Q9NZN3)
EH domain-containing protein 3 (PAST homolog 3)
Gene: EHD3

Interactor 2: ANFY1 (Q9P2R3)
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)
Gene: ANKFY1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	27189942
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005769 - early endosome GO:0005829 - cytosol GO:0006897 - endocytosis GO:0010008 - endosome membrane and 1 others more... GO:0090160 - Golgi to lysosome transport
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 1169
+	Hs
		1331788 EHD1_HUMAN (1-532): 0: 787: 87.03		ANFY1_HUMAN (1-1169): 0: 717: 100.00
+	Hs
		965155 EHD1_HUMAN (1-532): 0: 787: 87.03		ANK2_HUMAN (2-789): 1.44e-127: 435: 18.85
+	Hs
		965166 EHD3_HUMAN (1-535): 0: 776: 100.00		ANK2_HUMAN (2-789): 1.44e-127: 435: 18.85
+	Hs
		965151 EHD4_HUMAN (1-532): 0: 757: 75.14		ANK2_HUMAN (2-789): 1.44e-127: 435: 18.85
+	Hs
		965167 EHD2_HUMAN (1-532): 0: 749: 70.95		ANK2_HUMAN (2-789): 1.44e-127: 435: 18.85
+	Mm
		1208059 EHD1_MOUSE (1-532): 0: 788: 86.84		ANK2_MOUSE (875-1138): 1.56e-54: 211: 18.58
+	Mm
		1208057 EHD3_MOUSE (1-535): 0: 772: 97.38		ANK2_MOUSE (875-1138): 1.56e-54: 211: 18.58
+	Mm
		1208055 EHD4_MOUSE (1-532): 0: 767: 74.95		ANK2_MOUSE (875-1138): 1.56e-54: 211: 18.58
+	Mm
		1206516 EHD2_MOUSE (1-534): 0: 745: 70.69		ANK2_MOUSE (875-1138): 1.56e-54: 211: 18.58
+	Hs
		787897 EPS15_HUMAN (360-532): 1.63e-36: 146: 31.03		ANK2_HUMAN (2-789): 1.44e-127: 435: 18.85
+	Hs
		1021469 EP15R_HUMAN (360-534): 4.78e-34: 139: 30.11		ANK3_HUMAN (1-386): 1.03e-34: 147: 17.88
+	Hs
		257713 ITSN2_HUMAN (428-528): 2.18e-35: 143: 37.62		ANR17_HUMAN (28-434): 4.25e-27: 122: 12.96