HitPredict

Interactor 1: TBC25 (Q3MII6)
TBC1 domain family member 25
Gene: TBC1D25

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	21383079
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0006914 - autophagy GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 688 Hs			1 125
+	Hs
		1187138 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952196 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328037 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1187135 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1187137 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1416801 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		1416800 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1349323 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		952254 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328077 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1349321 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1349327 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1287256 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Dm
		1472745 Q9VPL5_DROME (112-475): 1.8e-78: 266: 27.08		Q9VEG5_DROME (1-120): 1.37e-50: 158: 29.17
+	Hs
		1428363 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1195313 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		1287255 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1433200 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		1195312 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1430332 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46