HitPredict

Interactor 1: TBC25 (Q3MII6)
TBC1 domain family member 25
Gene: TBC1D25

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 688 Hs			1 147
+	Hs
		328037 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26
+	Hs
		952196 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98
+	Hs
		1187138 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1187136 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		1187137 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		1349321 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3C_HUMAN (1-147): 4.66e-72: 214: 100.00
+	Hs
		1416801 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1416800 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		328077 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26
+	Hs
		952254 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98
+	Hs
		1349323 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		1349327 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Dm
		1472745 Q9VPL5_DROME (112-475): 1.8e-78: 266: 27.08		Q9VEG5_DROME (13-126): 2.3e-51: 160: 38.60
+	Hs
		1287256 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1287255 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		1195313 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1195312 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47
+	Hs
		1433200 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17
+	Hs
		1428363 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55
+	Hs
		1430332 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		GBRL1_HUMAN (13-126): 4.78e-52: 162: 39.47