HitPredict

Interactor 1: SRGP1 (Q91Z69)
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)
Gene: Srgap1

Interactor 2: RHOA (Q9QUI0)
Transforming protein RhoA (EC 3.6.5.2)
Gene: RHOA

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11672528
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007266 - Rho protein signal transduction GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1062 Mm			1 193
+	Mm
		953811 SRGP1_MOUSE (1-1062): 0: 675: 100.00		CDC42_MOUSE (1-193): 1.23e-76: 229: 52.33
+	Hs
		962215 SRGP1_HUMAN (1-1062): 0: 664: 94.84		RHOA_HUMAN (1-193): 5.82e-81: 240: 99.48
+	Hs
		988485 SRGP1_HUMAN (1-1062): 0: 664: 94.84		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		269537 SRGP2_HUMAN (1-1062): 0: 591: 67.07		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		269533 SRGP2_HUMAN (1-1062): 0: 591: 67.07		RAC3_HUMAN (1-179): 8.03e-74: 222: 57.54
+	Hs
		212765 SRGP3_HUMAN (1-1024): 0: 575: 64.86		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		988277 RHG04_HUMAN (1-910): 1.48e-130: 421: 41.37		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Dm
		828028 CDGAP_DROME (443-1053): 6.01e-107: 370: 18.66		RAC1_DROME (1-193): 1.89e-77: 231: 54.12
+	Hs
		962580 GMIP_HUMAN (44-859): 1.34e-89: 310: 15.44		RHOA_HUMAN (1-193): 5.82e-81: 240: 99.48
+	Hs
		988781 GMIP_HUMAN (44-859): 1.34e-89: 310: 15.44		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		988510 RHG12_HUMAN (375-671): 1.21e-88: 305: 25.33		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		955698 GMIP_HUMAN (44-859): 1.34e-89: 310: 15.44		CDC42_HUMAN (1-193): 1.23e-76: 229: 52.33
+	Hs
		962142 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RHOA_HUMAN (1-193): 5.82e-81: 240: 99.48
+	Hs
		988431 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RAC1_HUMAN (1-193): 6.82e-80: 237: 57.22
+	Hs
		978145 RHG12_HUMAN (375-671): 1.21e-88: 305: 25.33		RHOB_HUMAN (1-191): 7.04e-74: 222: 83.94
+	Hs
		1015505 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RHOG_HUMAN (1-193): 4.06e-77: 230: 54.40
+	Hs
		581097 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RAC2_HUMAN (1-193): 1.51e-76: 229: 53.61
+	Hs
		955270 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		CDC42_HUMAN (1-193): 1.23e-76: 229: 52.33
+	Hs
		953496 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RAC3_HUMAN (1-179): 8.03e-74: 222: 57.54
+	Hs
		978067 RHG21_HUMAN (331-1021): 2.62e-82: 296: 17.87		RHOB_HUMAN (1-191): 7.04e-74: 222: 83.94