HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: CDGAP (Q9VIS1)
GTPase-activating protein CdGAPr (d-CdGAPr)
Gene: CdGAPr

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	15710747
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 1843
+	Mm
		988897 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		RHG32_MOUSE (45-1534): 1.29e-103: 372: 23.33
+	Hs
		67650 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG32_HUMAN (85-1486): 1.31e-100: 362: 22.82
+	Hs
		156404 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG33_HUMAN (92-1408): 7.87e-94: 336: 24.96
+	Hs
		988402 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG44_HUMAN (202-999): 2.25e-94: 327: 16.12
+	Hs
		65907 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG42_HUMAN (118-937): 7.98e-90: 315: 15.87
+	Hs
		260707 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		OPHN1_HUMAN (117-833): 8.38e-88: 308: 13.89
+	Hs
		269537 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		SRGP2_HUMAN (191-985): 2.21e-82: 297: 15.89
+	Hs
		988407 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG31_HUMAN (402-1154): 3.52e-79: 292: 22.12
+	Hs
		988431 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG21_HUMAN (333-1131): 2.69e-77: 287: 17.45
+	Hs
		212765 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		SRGP3_HUMAN (191-948): 1.9e-77: 282: 14.96
+	Hs
		988277 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG04_HUMAN (192-863): 8.85e-76: 275: 16.93
+	Hs
		586979 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		CHIN_HUMAN (412-618): 6.84e-76: 262: 36.06
+	Hs
		914009 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		CHIO_HUMAN (405-618): 2.66e-74: 258: 34.42
+	Hs
		988328 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG05_HUMAN (112-638): 1.31e-67: 255: 16.13
+	Hs
		988417 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RHG15_HUMAN (224-623): 4.27e-71: 249: 22.69
+	Mm
		988900 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		RHG22_MOUSE (415-746): 8.63e-69: 248: 21.83
+	Mm
		988887 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		ABR_MOUSE (54-635): 1.19e-66: 246: 16.64
+	Mm
		988896 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		CHIO_MOUSE (412-618): 3.43e-70: 241: 33.65
+	Hs
		539995 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		BCR_HUMAN (399-591): 2.11e-19: 97.8: 36.41
+	Mm
		988892 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		BCR_MOUSE (399-591): 2.02e-19: 97.8: 36.41