HitPredict

Interactor 1: Q9VCH4 (Q9VCH4)
Myoblast city
Gene: mbc

Interactor 2: CRK (Q9XYM0)
Adapter molecule Crk
Gene: CRK

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.815

Property	Details
Experiments	17030600, 15457211
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	DOCK_N~SH3_2
Common GO terms	GO:0007520 - myoblast fusion GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1970 Dm			1 271
+	Hs
		802881 DOCK2_HUMAN (1-1810): 0: 2038: 38.35		CRKL_HUMAN (4-267): 5.07e-52: 173: 42.72
+	Hs
		802842 DOCK1_HUMAN (1-1901): 0: 1976: 38.98		CRKL_HUMAN (4-267): 5.07e-52: 173: 42.72
+	Hs
		802596 DOCK1_HUMAN (1-1901): 0: 1976: 38.98		CRK_HUMAN (4-266): 2.13e-51: 172: 43.48
+	Hs
		548738 DOCK2_HUMAN (1-1810): 0: 2038: 38.35		VAV_HUMAN (159-257): 2.99e-14: 74.4: 23.00
+	Hs
		802906 DOCK5_HUMAN (1-1900): 0: 1916: 35.94		CRKL_HUMAN (4-267): 5.07e-52: 173: 42.72
+	Hs
		802731 DOCK5_HUMAN (1-1900): 0: 1916: 35.94		CRK_HUMAN (4-266): 2.13e-51: 172: 43.48
+	Mm
		1141146 DOCK1_MOUSE (1-1900): 0: 2006: 38.79		GRB2_MOUSE (204-256): 1.67e-12: 67: 27.78
+	Hs
		412190 DOCK1_HUMAN (1-1901): 0: 1976: 38.98		FYN_HUMAN (112-239): 9.59e-14: 72.8: 21.21
+	Hs
		924565 DOCK1_HUMAN (1-1901): 0: 1976: 38.98		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		522979 DOCK1_HUMAN (1-1901): 0: 1976: 38.98		SRC_HUMAN (157-265): 2.41e-10: 62.4: 10.62
+	Hs
		924868 DOCK5_HUMAN (1-1900): 0: 1916: 35.94		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		802655 DOCK3_HUMAN (3-1964): 0: 1803: 29.80		CRK_HUMAN (4-266): 2.13e-51: 172: 43.48
+	Hs
		924698 DOCK4_HUMAN (3-1953): 0: 1816: 28.95		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		1078864 DOCK4_HUMAN (3-1953): 0: 1816: 28.95		ITSN1_HUMAN (177-259): 3.55e-11: 65.4: 18.07
+	Hs
		412257 DOCK3_HUMAN (3-1964): 0: 1803: 29.80		FYN_HUMAN (112-239): 9.59e-14: 72.8: 21.21
+	Hs
		924695 DOCK3_HUMAN (3-1964): 0: 1803: 29.80		GRB2_HUMAN (204-256): 1.59e-12: 67: 27.78
+	Hs
		523056 DOCK3_HUMAN (3-1964): 0: 1803: 29.80		SRC_HUMAN (157-265): 2.41e-10: 62.4: 10.62
+	Ce
		107035 G5EEN3_CAEEL (14-1784): 0: 1481: 25.38		CED2_CAEEL (2-256): 9.44e-42: 146: 32.84
+	Dm
		1228832 Q8MQW7_DROME (679-1970): 0: 1338: 100.00		CRK_DROME (1-271): 1.3e-71: 222: 100.00
+	Hs
		1200139 PHLB1_HUMAN (1625-1963): 4.29e-45: 181: 14.64		SH3K1_HUMAN (157-268): 1.22e-16: 81.2: 17.54