HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: CD27 (P26842)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9582383
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007166 - cell surface receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 260
+	Hs
		136662 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR5_HUMAN (6-256): 9.86e-60: 192: 22.52
+	Mm
		999816 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR14_MOUSE (9-250): 4.77e-49: 164: 17.32
+	Mm
		204646 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR11_MOUSE (4-211): 3.83e-45: 161: 20.00
+	Hs
		136737 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR11_HUMAN (17-214): 2.78e-39: 145: 19.09
+	Hs
		136666 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR3_HUMAN (4-183): 4.02e-38: 139: 20.69
+	Mm
		693162 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR5_MOUSE (6-256): 2.06e-59: 191: 20.77
+	Hs
		136714 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR14_HUMAN (6-215): 9.84e-34: 125: 19.55
+	Hs
		136656 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR16_HUMAN (17-183): 4.02e-31: 121: 19.88
+	Mm
		894452 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR3_MOUSE (30-183): 2.35e-31: 121: 22.29
+	Mm
		204649 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR11_MOUSE (4-211): 3.83e-45: 161: 20.00
+	Hs
		136664 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR8_HUMAN (28-190): 1.32e-22: 98.4: 14.54
+	Hs
		136668 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR4_HUMAN (30-183): 3.8e-21: 91.4: 20.38
+	Hs
		136683 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR9_HUMAN (40-183): 6.78e-21: 90.3: 20.00
+	Hs
		622601 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1A_HUMAN (27-260): 1.97e-40: 146: 20.49
+	Hs
		630265 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1B_HUMAN (13-174): 1.54e-36: 136: 19.77
+	Hs
		136729 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR19_HUMAN (9-155): 2.04e-12: 68.3: 20.78
+	Mm
		894453 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR3_MOUSE (30-183): 2.35e-31: 121: 22.29
+	Hs
		466573 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR16_HUMAN (17-183): 4.02e-31: 121: 19.88
+	Mm
		866565 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR4_MOUSE (30-183): 2.64e-23: 97.2: 23.57
+	Mm
		630395 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR9_MOUSE (37-193): 8.05e-21: 90.3: 20.89