HitPredict

Interactor 1: SSP1B (O01683)
FACT complex subunit ssrp1-B (Facilitates chromatin transcription complex subunit ssrp1-B) (HMG box-containing protein 3) (Structure-specific recognition protein 1-B)
Gene: hmg-3

Interactor 2: H4 (P62784)
Histone H4
Gene: his-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35297663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 689 Ce			1 103
+	Hs
		917167 SSRP1_HUMAN (3-687): 0: 710: 36.90		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Ce
		784738 SSP1A_CAEEL (1-630): 0: 684: 77.62		H4_CAEEL (1-103): 7.75e-49: 152: 100.00
+	Sc
		356709 POB3_YEAST (3-515): 0: 547: 25.53		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Hs
		917780 CIC_HUMAN (412-689): 2.25e-39: 158: 13.90		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		917971 HM20A_HUMAN (478-675): 7.03e-35: 137: 21.57		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		175766 HMGB3_HUMAN (476-645): 1.35e-30: 121: 20.93		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		918056 HM20B_HUMAN (532-629): 3.92e-26: 111: 28.43		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Sc
		356507 RT106_YEAST (337-543): 3.96e-29: 122: 19.07		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Sc
		356199 NHP6B_YEAST (539-631): 1.98e-27: 108: 33.68		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Sc
		356198 NHP6A_YEAST (544-629): 3.9e-26: 104: 37.50		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Hs
		449647 HMGB1_HUMAN (553-687): 1.8e-14: 74.8: 23.02		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		643301 HMGB2_HUMAN (553-687): 6.02e-14: 73.3: 24.46		H4_HUMAN (1-103): 3.12e-48: 150: 99.03