HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TNR4 (P43489)
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Gene: TNFRSF4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.579

Property	Details
Experiments	9488716, 15941918
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 277
+	Mm
		204646 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59
+	Mm
		866565 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR4_MOUSE (23-277): 8.86e-64: 203: 62.26
+	Hs
		136737 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR11_HUMAN (28-181): 3.63e-36: 137: 26.40
+	Hs
		136662 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR5_HUMAN (9-175): 7.07e-38: 136: 25.52
+	Hs
		136656 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR16_HUMAN (31-244): 6.57e-36: 134: 25.40
+	Hs
		136666 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR3_HUMAN (11-180): 2.19e-35: 133: 22.86
+	Hs
		136714 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR14_HUMAN (6-165): 6.8e-31: 118: 23.53
+	Mm
		894452 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR3_MOUSE (32-194): 4.23e-31: 121: 25.39
+	Mm
		999816 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR14_MOUSE (12-169): 2.49e-32: 121: 28.65
+	Hs
		136683 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR9_HUMAN (43-185): 8.18e-27: 106: 25.00
+	Hs
		136663 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		CD27_HUMAN (12-144): 2.56e-24: 100: 27.94
+	Hs
		136729 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR19_HUMAN (7-140): 2.11e-22: 97.6: 20.98
+	Hs
		136664 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR8_HUMAN (30-203): 6.62e-20: 91.1: 21.62
+	Mm
		204649 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR11_MOUSE (6-181): 1.18e-41: 153: 27.59
+	Hs
		630265 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1B_HUMAN (21-248): 5.87e-43: 154: 22.10
+	Mm
		693162 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR5_MOUSE (9-175): 1.08e-37: 136: 23.44
+	Hs
		466573 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR16_HUMAN (31-244): 6.57e-36: 134: 25.40
+	Mm
		894453 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR3_MOUSE (32-194): 4.23e-31: 121: 25.39
+	Hs
		622601 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1A_HUMAN (14-198): 1.66e-32: 125: 18.65
+	Mm
		630395 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR9_MOUSE (43-183): 1.24e-21: 93: 24.52