HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TNR8 (P28908)
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Gene: TNFRSF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	8999898, 9511754, 11971184
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 595
+	Hs
		136666 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR3_HUMAN (3-289): 1.09e-46: 171: 18.83
+	Mm
		894452 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR3_MOUSE (13-289): 4.45e-40: 153: 19.61
+	Mm
		204646 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR11_MOUSE (11-202): 7.6e-37: 147: 21.00
+	Hs
		136737 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR11_HUMAN (23-202): 3.53e-33: 136: 20.75
+	Hs
		136662 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR5_HUMAN (18-201): 6.3e-35: 135: 18.75
+	Mm
		999816 TRAF5_MOUSE (1-557): 2.64e-146: 434: 79.57		TNR14_MOUSE (24-192): 5.22e-35: 135: 23.30
+	Hs
		136714 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR14_HUMAN (20-174): 1e-32: 128: 21.38
+	Hs
		630265 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1B_HUMAN (12-350): 1.61e-53: 190: 19.83
+	Hs
		136668 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR4_HUMAN (39-233): 2.75e-27: 113: 16.99
+	Hs
		136683 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR9_HUMAN (45-207): 1.13e-25: 108: 16.37
+	Hs
		136663 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		CD27_HUMAN (1-122): 1.72e-21: 96.1: 20.80
+	Mm
		894453 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR3_MOUSE (13-289): 4.45e-40: 153: 19.61
+	Hs
		622601 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR1A_HUMAN (22-332): 2.03e-41: 157: 17.46
+	Mm
		204649 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR11_MOUSE (11-202): 7.6e-37: 147: 21.00
+	Hs
		136729 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR19_HUMAN (30-133): 6.69e-16: 82.3: 17.27
+	Hs
		136656 TRAF5_HUMAN (1-557): 4.4e-148: 439: 100.00		TNR16_HUMAN (20-133): 8.35e-14: 75.7: 21.19
+	Mm
		693162 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR5_MOUSE (28-201): 1.73e-35: 137: 18.13
+	Mm
		866565 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR4_MOUSE (36-235): 1.1e-31: 125: 16.11
+	Mm
		630395 TRAF3_MOUSE (2-556): 4.47e-124: 377: 41.27		TNR9_MOUSE (40-205): 1.65e-26: 110: 16.67
+	Hs
		466573 TRAF3_HUMAN (4-556): 6.39e-122: 372: 41.06		TNR16_HUMAN (20-133): 8.35e-14: 75.7: 21.19