HitPredict

Interactor 1: ARC1A (Q92747)
Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
Gene: ARPC1A

Interactor 2: COR2B (Q9UQ03)
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Gene: CORO2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DUF1899~WD40, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0003779 - actin binding GO:0015629 - actin cytoskeleton GO:0030036 - actin cytoskeleton organization GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 370 Hs			1 480
+	Hs
		179268 ARC1B_HUMAN (1-369): 1.91e-83: 260: 68.10		COR2B_HUMAN (1-480): 1.03e-130: 388: 100.00
+	Hs
		179266 ARC1B_HUMAN (1-369): 1.91e-83: 260: 68.10		COR1C_HUMAN (9-473): 3.92e-115: 348: 44.63
+	Hs
		724411 POC1B_HUMAN (127-363): 1.44e-46: 166: 13.96		COR1A_HUMAN (9-476): 3.15e-110: 335: 43.76
+	Hs
		1246423 POC1A_HUMAN (1-123): 7.59e-29: 117: 15.45		CORO6_HUMAN (9-477): 8.64e-118: 355: 45.03
+	Hs
		724407 POC1A_HUMAN (1-123): 7.59e-29: 117: 15.45		COR1A_HUMAN (9-476): 3.15e-110: 335: 43.76
+	Hs
		1334151 POC1B_HUMAN (127-363): 1.44e-46: 166: 13.96		POC1A_HUMAN (3-301): 3.06e-74: 241: 13.20
+	Hs
		179238 ARC1B_HUMAN (1-369): 1.91e-83: 260: 68.10		FBXW7_HUMAN (19-161): 1.27e-13: 75.4: 13.33
+	Mm
		988931 LIS1_MOUSE (186-365): 2.78e-34: 132: 17.20		LIS1_MOUSE (133-410): 9.18e-58: 198: 12.12
+	Dm
		1463899 WDS_DROME (1-235): 2.53e-52: 179: 12.50		WDS_DROME (211-449): 1.49e-33: 131: 10.98
+	Hs
		965071 WDR5B_HUMAN (1-231): 1.24e-51: 176: 12.71		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	At
		1247477 TAF5_ARATH (51-359): 4.44e-15: 78.7: 12.62		TAF5_ARATH (40-339): 8.7e-64: 220: 15.92
+	Hs
		965151 SNR40_HUMAN (129-369): 2.38e-45: 160: 14.52		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Hs
		845264 LIS1_HUMAN (186-365): 3.44e-34: 132: 17.20		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Hs
		302801 CIAO1_HUMAN (2-131): 1.49e-23: 101: 13.82		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Sc
		793963 COPA_YEAST (3-330): 1.29e-23: 104: 10.55		TAF5_YEAST (172-345): 5.72e-21: 98.1: 9.90
+	Sc
		793908 TAF5_YEAST (1-161): 3.84e-20: 94.2: 13.10		TAF5_YEAST (172-345): 5.72e-21: 98.1: 9.90
+	Hs
		1149764 TAF5_HUMAN (143-357): 1.05e-17: 86.8: 19.40		TAF5_HUMAN (181-345): 5.78e-19: 92: 11.22
+	Hs
		1410246 TBL1Y_HUMAN (41-359): 1.22e-24: 106: 13.29		TBL1R_HUMAN (85-216): 1.05e-12: 72: 27.86
+	Hs
		261440 TBL1X_HUMAN (87-359): 3.75e-19: 90.7: 15.36		TBL1R_HUMAN (85-216): 1.05e-12: 72: 27.86