HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	15388328
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 718
+	Hs
		1110227 HDAC1_HUMAN (1-443): 0: 642: 90.07		MD1L1_HUMAN (1-718): 2.01e-61: 221: 100.00
+	Mm
		148740 HDAC1_MOUSE (1-443): 0: 645: 90.29		MD1L1_MOUSE (1-716): 8.61e-60: 216: 80.31
+	Hs
		1109803 HDAC1_HUMAN (1-443): 0: 642: 90.07		MRCKA_HUMAN (164-708): 5.55e-43: 170: 17.69
+	Hs
		773240 HDAC2_HUMAN (1-488): 0: 707: 100.00		MYH10_HUMAN (272-717): 2.03e-20: 99: 11.92
+	Hs
		157696 HDAC2_HUMAN (1-488): 0: 707: 100.00		CTRO_HUMAN (54-632): 5.19e-13: 75: 15.98
+	Hs
		772937 HDAC2_HUMAN (1-488): 0: 707: 100.00		MYH9_HUMAN (421-715): 4.48e-10: 65.4: 11.53
+	Hs
		563054 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH8_HUMAN (289-716): 1.68e-17: 89.7: 12.93
+	Hs
		1110177 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH2_HUMAN (1-440): 9.58e-16: 83.9: 9.23
+	Hs
		157335 HDAC1_HUMAN (1-443): 0: 642: 90.07		CTRO_HUMAN (54-632): 5.19e-13: 75: 15.98
+	Hs
		556922 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH7_HUMAN (421-698): 2.07e-12: 73.1: 11.15
+	Hs
		556850 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH1_HUMAN (375-705): 8.43e-11: 67.8: 12.95
+	Hs
		1110225 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH4_HUMAN (375-694): 2.24e-10: 66.6: 11.49
+	Hs
		772785 HDAC1_HUMAN (1-443): 0: 642: 90.07		MYH9_HUMAN (421-715): 4.48e-10: 65.4: 11.53
+	Mm
		1223386 HDAC6_MOUSE (11-367): 2.94e-104: 338: 24.12		MYH10_MOUSE (238-718): 4.83e-22: 104: 10.75
+	Hs
		773296 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		MYH10_HUMAN (272-717): 2.03e-20: 99: 11.92
+	Hs
		776867 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		MYH11_HUMAN (3-364): 4.2e-11: 68.9: 10.50
+	Hs
		773060 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		MYH9_HUMAN (421-715): 4.48e-10: 65.4: 11.53
+	Hs
		587833 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		1458572 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		MRCKB_HUMAN (1-389): 1.44e-09: 63.8: 11.96
+	Hs
		1365609 HDAC6_HUMAN (11-363): 6.97e-102: 332: 24.04		MY18A_HUMAN (44-521): 2.61e-09: 63: 15.87