HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 1163
+	Hs
		1129671 CBP_HUMAN (1-2442): 0: 1096: 100.00		MDC1_HUMAN (20-908): 7.61e-38: 157: 10.83
+	Hs
		1130587 CBP_HUMAN (1-2442): 0: 1096: 100.00		NCOA6_HUMAN (30-1014): 1.7e-13: 77.8: 9.55
+	Hs
		180953 TIF1A_HUMAN (667-1202): 2.18e-34: 147: 17.97		AFF4_HUMAN (1-1163): 1.68e-129: 427: 100.00
+	Hs
		1324491 CHD7_HUMAN (105-479): 4.97e-11: 71: 9.19		AN36B_HUMAN (543-1125): 1.1e-70: 261: 8.70
+	Hs
		1129788 TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64		MDC1_HUMAN (20-908): 7.61e-38: 157: 10.83
+	Hs
		1129599 BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89		MDC1_HUMAN (20-908): 7.61e-38: 157: 10.83
+	Hs
		674162 BRD2_HUMAN (1065-1195): 9.69e-34: 143: 30.53		MDC1_HUMAN (20-908): 7.61e-38: 157: 10.83
+	Mm
		107090 TRI33_MOUSE (614-1207): 5.1e-36: 152: 13.99		F8VPR5_MOUSE (47-725): 2.2e-32: 139: 12.59
+	Hs
		1106190 BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89		MYO9B_HUMAN (494-931): 3.57e-26: 119: 13.15
+	Hs
		1141173 BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89		NIPBL_HUMAN (91-887): 9.34e-18: 91.6: 16.10
+	Hs
		1067330 EP300_HUMAN (1789-2434): 7.34e-09: 63.6: 13.61		MDC1_HUMAN (20-908): 7.61e-38: 157: 10.83
+	Hs
		1395227 TRI33_HUMAN (614-1207): 1.09e-36: 154: 13.64		CHAP1_HUMAN (29-572): 1.07e-09: 65: 11.56
+	Hs
		674271 BRD2_HUMAN (1065-1195): 9.69e-34: 143: 30.53		TITIN_HUMAN (209-918): 2.18e-11: 70.8: 8.61
+	Hs
		1141264 BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89		CHAP1_HUMAN (29-572): 1.07e-09: 65: 11.56
+	Hs
		1141227 BRD3_HUMAN (1073-1195): 1.37e-33: 143: 30.89		THOC2_HUMAN (501-879): 3.94e-09: 63.5: 14.63
+	Mm
		74238 EP300_MOUSE (1833-2294): 4.11e-09: 64.8: 13.89		F8VPR5_MOUSE (47-725): 2.2e-32: 139: 12.59
+	Dm
		119660 M9PB30_DROME (1836-2241): 2.87e-17: 91.8: 13.38		M9PB30_DROME (553-1072): 2.33e-11: 70.9: 7.97
+	Hs
		1130579 KMT2C_HUMAN (1839-2361): 2.29e-10: 68.7: 10.22		NCOA6_HUMAN (30-1014): 1.7e-13: 77.8: 9.55
+	Mm
		1455913 PCLO_MOUSE (9-1091): 4.6e-11: 71: 8.82		PCLO_MOUSE (601-1091): 1.52e-11: 71.6: 8.35
+	Hs
		1287954 PB1_HUMAN (1040-1195): 4.73e-12: 74.4: 19.87		THOC2_HUMAN (501-879): 3.94e-09: 63.5: 14.63