Interactor 1: NR5A2 (O00482)
Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1)
Gene: NR5A2

Interactor 2: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.833

The method score is based on:

Property Details
Experiments 15604093, 23975195, 22504882
Identification Methods two hybrid, fluorescence polarization spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~SRC-1
Common GO terms GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 11Aug2025