Interactor 1: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.938

The method score is based on:

Property Details
Experiments 28561026, 11080158, 21988832, 17353931, 22748767, 10966108
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TIP49~TIP49, TIP49~TIP49_C
Common GO terms GO:0000723 - telomere maintenance
GO:0000492 - box C/D snoRNP assembly
GO:0000786 - nucleosome
GO:0000791 - euchromatin
GO:0000812 - Swr1 complex
and 56 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 463
Hs

1 463
+ Mm
+ Rn
+ Xl
+ Mm
+ Hs
+ Xl
+ Xl
+ Hs
+ At
+ Sc
+ Dm
+ Tt
+ Sc
+ Ce

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Last updated: 15 Jul 2024