HitPredict

Interactor 1: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Interactor 2: FSD1 (Q9BTV5)
Fibronectin type III and SPRY domain-containing protein 1 (MID1-related protein 1) (Microtubule-associated protein GLFND)
Gene: FSD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 496
+	Hs
		186570 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI18_HUMAN (1-485): 4.82e-104: 326: 26.94
+	Hs
		186577 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRI18_HUMAN (1-485): 4.82e-104: 326: 26.94
+	Hs
		1381218 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRIM1_HUMAN (1-493): 7.59e-99: 315: 25.42
+	Hs
		1397303 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRIM1_HUMAN (1-493): 7.59e-99: 315: 25.42
+	Hs
		186599 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		TRI18_HUMAN (1-485): 4.82e-104: 326: 26.94
+	Hs
		1381205 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI39_HUMAN (9-481): 1.25e-94: 298: 14.46
+	Hs
		572110 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI27_HUMAN (2-494): 6.08e-95: 298: 13.56
+	Hs
		1397295 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRI39_HUMAN (9-481): 1.25e-94: 298: 14.46
+	Hs
		572141 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRI27_HUMAN (2-494): 6.08e-95: 298: 13.56
+	Hs
		572291 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		TRI27_HUMAN (2-494): 6.08e-95: 298: 13.56
+	Hs
		142694 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI38_HUMAN (16-475): 2.27e-83: 267: 14.01
+	Hs
		142698 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRI38_HUMAN (16-475): 2.27e-83: 267: 14.01
+	Hs
		142704 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		TRI38_HUMAN (16-475): 2.27e-83: 267: 14.01
+	Hs
		1294323 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI50_HUMAN (19-470): 1.17e-72: 240: 12.96
+	Hs
		1294325 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		TRI50_HUMAN (19-470): 1.17e-72: 240: 12.96
+	Hs
		1125266 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		TRI25_HUMAN (3-469): 8.08e-77: 254: 18.49
+	Hs
		1381194 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI62_HUMAN (31-464): 1.37e-68: 228: 17.94
+	Hs
		1380801 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI63_HUMAN (4-161): 1.27e-49: 175: 27.04
+	Hs
		1381197 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI54_HUMAN (2-163): 3.24e-34: 133: 22.70
+	Hs
		1381198 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		TRI55_HUMAN (1-163): 4.61e-32: 131: 21.95