HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Property	Details
Experiments	28514442, 31980649, 33961781, 19531213, 17255943, 15090612, unassigned2173, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_9, SH3_9~SH3_9
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 1129
+	Hs
		1461575 CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36		ASAP1_HUMAN (17-1129): 0: 826: 100.00
+	Hs
		207923 Q5JPT6_HUMAN (1-665): 1.57e-126: 391: 100.00		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		207931 SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		988022 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		ASAP1_HUMAN (17-1129): 0: 826: 100.00
+	Hs
		594133 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		ASAP1_HUMAN (17-1129): 0: 826: 100.00
+	Hs
		207918 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		207910 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		207897 NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24		ASAP2_HUMAN (21-967): 0: 644: 55.31
+	Hs
		987790 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		ASAP3_HUMAN (21-913): 8e-175: 539: 44.27
+	Hs
		1384245 SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00		ARAP1_HUMAN (368-620): 3.84e-58: 222: 24.90
+	Hs
		987649 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		ACAP1_HUMAN (45-688): 1.13e-152: 475: 20.79
+	Hs
		1359631 SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00		ARAP3_HUMAN (368-605): 4.8e-56: 215: 27.46
+	Hs
		594002 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		ACAP1_HUMAN (45-688): 1.13e-152: 475: 20.79
+	Hs
		1359652 CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36		ARAP3_HUMAN (368-605): 4.8e-56: 215: 27.46
+	Hs
		49975 SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00		RHG10_HUMAN (908-1127): 1.4e-15: 84.1: 16.29
+	Hs
		1216109 SPD2A_HUMAN (3-650): 8.88e-37: 150: 16.74		AGAP1_HUMAN (361-662): 3.34e-62: 230: 28.30
+	Hs
		987873 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		ARAP1_HUMAN (368-620): 3.84e-58: 222: 24.90
+	Hs
		1121947 ARHG7_HUMAN (2-595): 6.82e-34: 140: 16.23		GIT2_HUMAN (446-1074): 4.14e-57: 213: 16.98
+	Hs
		594083 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		ARAP1_HUMAN (368-620): 3.84e-58: 222: 24.90
+	Hs
		593994 NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62		GIT2_HUMAN (446-1074): 4.14e-57: 213: 16.98