Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Interactor 2: ARAP1 (Q96P48)
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)
Gene: ARAP1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.958 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 31980649, 33961781, 19380743, unassigned2173, 21706016, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, RhoGAP~SH3_1 |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
