HitPredict

Interactor 1: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Interactor 2: PIAS3 (Q9Y6X2)
E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)
Gene: PIAS3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 548 Hs			1 628
+	Hs
		1380897 TRI63_HUMAN (8-326): 1.5e-79: 255: 61.88		PIAS3_HUMAN (1-628): 0: 879: 100.00
+	Hs
		572303 TRI27_HUMAN (12-440): 3.64e-68: 230: 14.79		PIAS3_HUMAN (1-628): 0: 879: 100.00
+	Hs
		297684 TRI55_HUMAN (1-548): 7.73e-118: 360: 100.00		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		297864 TRI55_HUMAN (1-548): 7.73e-118: 360: 100.00		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		297667 TRI63_HUMAN (8-326): 1.5e-79: 255: 61.88		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		297685 TRIM5_HUMAN (13-396): 1.08e-70: 236: 13.82		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		297434 TRI27_HUMAN (12-440): 3.64e-68: 230: 14.79		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		297846 TRI63_HUMAN (8-326): 1.5e-79: 255: 61.88		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		297743 TRI27_HUMAN (12-440): 3.64e-68: 230: 14.79		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		572066 TRI27_HUMAN (12-440): 3.64e-68: 230: 14.79		PIAS4_HUMAN (2-477): 2.12e-177: 514: 46.71
+	Hs
		142689 TRI38_HUMAN (12-433): 1.33e-66: 225: 16.47		PIAS4_HUMAN (2-477): 2.12e-177: 514: 46.71
+	Hs
		297826 TRI67_HUMAN (122-326): 8.36e-14: 76.3: 24.39		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		1100526 TIF1B_HUMAN (18-534): 5.4e-67: 234: 15.37		ZMIZ1_HUMAN (79-422): 1.83e-84: 287: 24.93
+	Hs
		1256063 TRI67_HUMAN (122-326): 8.36e-14: 76.3: 24.39		ZMIZ1_HUMAN (79-422): 1.83e-84: 287: 24.93
+	Hs
		1254716 TRI67_HUMAN (122-326): 8.36e-14: 76.3: 24.39		ZMIZ2_HUMAN (81-619): 2.54e-79: 271: 20.46