Interactor 1: TRIM5 (Q9C035)
Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5)
Gene: TRIM5
Interactor 2: TRI35 (Q9UPQ4)
E3 ubiquitin-protein ligase TRIM35 (EC 2.3.2.27) (Hemopoietic lineage switch protein 5)
Gene: TRIM35
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16775307 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0044790 - suppression of viral release by host GO:0045087 - innate immune response and 1 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025